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Pharmacological group Metabolic agent.
Pharmacodynamics
Inosine - a derivative (nucleoside) of purine - a precursor of adenosine triphosphate (ATP). Refers to a group of drugs that regulate metabolic processes.
It has antihypoxic and antiarrhythmic effects. Increases the energy balance of the myocardium, improves coronary circulation, and prevents the consequences of intraoperative renal ischemia. It is directly involved in the metabolism of glucose and promotes the activation of metabolism under conditions of hypoxia and in the absence of ATP. It activates the metabolism of pyruvic acid, which is necessary to ensure the normal process of tissue respiration, and also promotes the activation of xanthine dehydrogenase. Stimulates the synthesis of nucleotides, enhances the activity of certain enzymes of the Krebs cycle. Penetrating into cells, it has a positive effect on metabolic processes in the myocardium - it increases the strength of heart contractions and promotes a more complete relaxation of the myocardium in diastole, as a result of which the stroke volume increases. The mechanism of antiarrhythmic action is not fully understood.
Reduces platelet aggregation, activates tissue regeneration (especially myocardium and mucous membrane of the gastrointestinal tract).
Indications for using Riboxin
In the complex therapy of ischemic heart disease (after myocardial infarction), myocardial dystrophy after an infectious disease, heart rhythm disturbances caused by the use of cardiac glycosides.
In the complex therapy of liver diseases (hepatitis, cirrhosis, fatty liver).
During surgery on an isolated kidney as a means of pharmacological protection in case of short-term shutdown of the blood circulation of the operated organ.
Method of administration and dosage of Riboxin
Inosine is administered orally before meals. The daily dose when taken orally in bodybuilding is 1.5 - 2.5 g. In the first days of admission, the daily dose of inosine is 0.6 - 0.8 g - 0.2 g 3 - 4 times a day. If the drug is well tolerated, this dose is increased to 2.5 g. The duration of the course is from 4 weeks to 1.5 - 3 months.
For intravenous drip, a solution of 20 mg / ml is diluted in 5% dextrose (glucose) solution or 0.9% sodium chloride solution (up to 250 ml).
Synonyms - Analogues: Inosine; Inosine-F; Riboxin; Riboxin-Vero; Riboksin-Darnitsa; Riboxin-LekT; Riboxin-PNITIA; Riboxin-UVI; Ribonosin.
Riboxin Effects
Inosine is a purine derivative, a precursor of adenosine triphostphatic acid (ATP), and is a vital source of energy in bodybuilding.
Inosine stimulates the synthesis of nucleotides, enhances the activity of some enzymes of the Krebs cycle.
As a nucleoside, inosine can penetrate cells and increase the energy balance of the myocardium.
Improves coronary circulation and metabolic processes in the myocardium. Riboxin has antihypoxic effect.
Recommendations for use Riboxin in sports
