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Pharmacodynamics
Mechanism of action. The active component of Likferr100, an iron-sucrose complex, consists of a core of a multinuclear iron (III) hydroxide surrounded by a large number of non-covalently bound sucrose molecules. The average molecular weight of this complex is approximately 43 kDa. The structure of the multinucleated iron-containing nucleus is similar to the structure of the ferritin protein nucleus, a physiological iron depot. This complex is designed to create a controlled source of utilized iron for proteins responsible for the transport and storage of iron in the body (transferrin and ferritin, respectively).
After intravenous administration, the multinucleated iron-containing nucleus of this complex is captured mainly by the reticuloendothelial system of the liver, spleen and bone marrow. At the next stage, iron is used for the synthesis of Hb, myoglobin and other iron-containing enzymes, or it is stored mainly in the liver in the form of ferritin.
Indications of the drug Likferr100
Treatment of iron deficiency conditions in the following cases:
- with a clinical need for a quick replenishment of iron stores;
- in patients who cannot tolerate oral iron preparations or do not adhere to the treatment regimen;
- in the presence of active inflammatory bowel disease, when oral iron supplements are ineffective.
Exercise is a great way to keep yourself in top shape and effectively deal with physical inactivity. Many are so addicted that they begin to train seriously. Playing sports at a confident amateur level or even at a professional level changes the body. He becomes more resilient, and it is also easier for a person to control his own limbs, his sense of balance improves, and immunity increases. Sports also increase hemoglobin: since muscles require more oxygen, the body adapts in this way.
However, certain changes are possible only when the lessons are really serious. That is, jogging in the morning or going to the fitness center 2 times a week does not count. This kind of workout really helps to keep yourself in shape. But they do not change the composition of the blood: this requires super-efforts.
But really serious loads can lead to an increase in hemoglobin. The norm for men and women increases by 10 points from 130 g / l and from 120 g / l, respectively. However, such changes occur when it comes to hours of study. And if a person stops training in this way, over time, his hemoglobin will return to the norm, which is typical for the majority.
How to identify low hemoglobin?
The problem of low hemoglobin in athletes is expressed in the fact that people who exercise regularly accumulate a certain supply of nutrients and the elements they need in general. Therefore, an iron deficiency state can make itself felt far from immediately.
And here there are 2 probabilities. Within one, the first symptoms will appear imperceptibly, not very pronounced. Most of these signs of pathology are overlooked, considering it to be something like a temporary minor malaise. This can become a separate problem, since it is desirable to correct the lack of iron immediately. But the neglected iron deficiency state will need to be removed for months. In difficult situations, it means hospitalization. And therapy takes time anyway.
Sometimes the athlete's body behaves differently: for a long time, health problems are not observed. And then suddenly "a whole bunch" of signs of anemia appears. In any case, we are talking about standard symptoms:
