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Pharmacological group Metabolic agent.
Pharmacodynamics
Pharmacological effects are due to the complex effect of the components included in the Cytoflavin preparation.
Succinic acid is an endogenous intracellular metabolite of the Krebs cycle, which performs a universal energy-synthesizing function in the cells of the body.
With the participation of the coenzyme flavina adenine dinucleotide (FAD), succinic acid is rapidly transformed by the mitochondrial enzyme succinate dehydrogenase into fumaric acid and then into other metabolites of the tricarboxylic acid cycle. Stimulates aerobic glycolysis and ATP synthesis in cells.
The end product of the metabolism of succinic acid in the Krebs cycle is carbon dioxide and water. Succinic acid improves tissue respiration by activating the transport of electrons in mitochondria.
Riboflavin (vitamin B2) is a FAD coenzyme that activates succinate dehydrogenase and other redox reactions of the Krebs cycle.
Nicotinamide (vitamin PP) is an amide of nicotinic acid. Nicotinamide in cells, through a cascade of biochemical reactions, is transformed into the form of nicotinamide adenine nucleotide (NAD) and its phosphate (NADP), activating nicotinamide-dependent enzymes of the Krebs cycle, which are necessary for cellular respiration and stimulation of ATP synthesis.
Inosine is a purine derivative, a precursor of ATP. Has the ability to activate a number of enzymes of the Krebs cycle, stimulating the synthesis of key enzymes-nucleotides: FAD and NAD.
Thus, all components of the Cytoflavin preparation are natural metabolites of the body and stimulate tissue respiration. Metabolic energy correction, antihypoxic and antioxidant activity of the drug, which determine its pharmacological properties and therapeutic efficacy, are due to the complementary action of succinic acid, inosine, nicotinamide and riboflavin.
Indications of the drug Cytoflavin
In adults in complex therapy:
Method of administration and dosage
Inside, 2 tables. 2 times a day with an interval between doses of 8-10 hours. The tablets should be taken at least 30 minutes before meals, without chewing, washed down with water (100 ml).
It is recommended to take the drug in the morning and afternoon (no later than 18 hours).
The duration of the course of treatment is 25 days. The appointment of a repeated course is possible with an interval of at least 1 month.